TNFAIP3 and systemic lupus erythematosus: In this study, we functionally characterized an enhancer ∼55 kb upstream of TNFAIP3 with two SNPs, rs58905141 and rs10499197, that have strong bioinformatic evidence of functionality and are shared by the ∼109 kb SLE risk haplotype and others (Ray et al., 2020).