To investigate whether RelA/p65 or CEBPB exhibited allele-specific binding to the enhancer region in native chromatin architecture, ChIP-qPCR was performed in EBV B cells homozygous for the TNFAIP3 SLE risk or non-risk haplotype using anti-p65 or anti-CEBPB antibodies and primers that flanked either the RelA/p65 or CEBPB binding motifs, respectively (Supplementary Table S4). This evidence concerns the gene RELA and systemic lupus erythematosus.