Through Cytoscape, we could summarize that CCL5, CCR7, CD2, CD27, CD274, CD3D, GNLY, GZMA, GZMH, GZMK, IL2RB, IL7R, ITK, KLRB1, and PRF1 were hub genes of sepsis (Figure 5). The gene discussed is PRF1; the disease is Sepsis.