Through Cytoscape, we could summarize that CCL5, CCR7, CD2, CD27, CD274, CD3D, GNLY, GZMA, GZMH, GZMK, IL2RB, IL7R, ITK, KLRB1, and PRF1 were hub genes of sepsis (Figure 5). The gene discussed is CD274; the disease is Sepsis.