IL18 and pancreatic adenocarcinoma: We plotted Kaplan-Meier plots to test whether the expression of  prognostic pyroptosis-related genes was correlated with the prognosis of PAAD. The results show that PAAD patients with high expression of NLRP1 had a better prognosis, while PAAD patients with low expression of NLRP2, GSDMC, IL18 and CASP4 had a better prognosis (Additional file 7: Fig.s S7A-E).