In addition, NMSC was associated with VD risk (0.20 [0.05–0.79]) among patients without ApoE4. Melanoma of skin cancer was associated with increased AD (2.77 [1.03–7.45]) and VD (4.48 [1.10–18.32]) risks among patients with BMI between 18 and 25, but NMSC was associated with ACD (0.66 [0.45–0.97]) risk among those with BMI between 25 and 30 (Supplementary Table 3). Here, APOE is linked to melanoma.