PRDM9 and neoplasm: In keeping with this, germline NUMTs were more likely to be found within 3 kb of a PRDM9-binding site (P = 0.003, permutation test), and tumour-specific NUMTs were more likely to be found within 1 kb of a PRDM9-binding site (P = 0.003, permutation test) (Fig. 5e and Extended Data Fig. 8c).