INS and type 2 diabetes mellitus: ,13 MS proteomics has been utilized in a spectrum of tissues to study multiple diseases spanning from cerebrospinal fluid for Alzheimer’s disease to brain for medulloblastoma to induced pluripotent stem cells differentiated into myoblasts for T2D.14, 15, 16 A recent review in insulin-target proteomics of various organs highlighted different pathological processes related to insulin resistance (IR).