Similar as have been shown in previous publications, neurohormone (BNP, NT-proBNP) and inflammatory factors (hs-CRP, TNF-α, IL-6, and IL-17) increased significantly (P < .05) in CHF patients, confirming the involvement of inflammation in the development of CHF (Fig. 2B and C). The gene discussed is IL6; the disease is congestive heart failure.