For instance, the aberrant expression of AP-2γ (as well as AP-2α and AP-2β) has been reported in breast cancer.[18] Particularly, AP-2γ are believed to play complex roles in the development of breast cancer.[19] In this mini review, we summarize the current knowledge about the role of AP-2γ in breast cancer progression and its potential as a drug target in breast cancer treatment. The gene discussed is TFAP2B; the disease is breast carcinoma.