VEGFA and Blindness: It was first described in the literature published in 1949 by Sorsby et al[1] and named after the leading author of this manuscript.[1] Patients with this condition may become symptomatic during their second decade of life, however, the average onset of the disease is usually during the fourth to fifth decade of life.[1,2] Prior to the era of anti-vascular endothelial growth (anti-VEGF) injections, SFD led to severe bilateral visual reduction and blindness.[1,2]