ADH1B and head and neck cancer: Further, the incidence of alcohol consumption is directly affiliated with the increased risk of head and neck cancers in Asian populations.[7] Lee et al,[8] identified that an affiliated genetic mutation of ethanol-metabolizing genes, specifically the genotypes of alcohol dehydrogenase 1B and alcohol dehydrogenase H2, results in the poor overall survival of diagnosed head and neck cancer patients in addition to exponentially increasing the risk of cancer development.