CATSPER1 and Infertility: These are among many other known ion channels implicated in maleinfertility, such as the proton voltage-gated ion channel (Hv1), potassiumvoltage-gated ion channel (SLO3/KCNU1), and sodium voltage-gated ion channel(NaV1.1-1.9).85 Of the 4 genes identified in the CATSPER family, 2 areresponsible for the infertility phenotype (CATPSER1 andCATSPER2).