SPTLC1 and amyotrophic lateral sclerosis: Mutations in the SPTLC1 gene are associated with peripheral neuronal dysfunction including hereditary sensory neuropathy type 1 (HSAN1) (Bejaoui et al., 2001; Dawkins et al., 2001), childhood amyotrophic lateral sclerosis (ALS) (Mohassel et al., 2021) and macular telengectasia type-2 (Gantner et al., 2019).