Additionally, because rapamycin inhibits adipogenesis, caution should be exercised while taking it in HGPS patients with global lipoatrophy and lipodystrophy [57].In vitro, sulforaphane which is an antioxidant produced from vegetables of the family Brassicaceae, has been shown to improve progerin removal by apoptosis and setbacks the cellular attributes presenting HGPS [58]. This evidence concerns the gene LMNA and Hutchinson-Gilford progeria syndrome.