CGAS and brain infarction: In addition, Qian et al. found that an oligodeoxynucleotide called A151, which contains the immunosuppressive motif TTAGGG, abrogates the activation of cytosolic nucleic acid-sensing cGAS and the AIM inflammasome by binding to these molecules in a manner that competes with immunostimulatory DNA and that A1515 decreases the volume of cerebral infarction and the number of dead cells by inhibiting the cGAS–STING signalling pathway in middle cerebral artery occlusion (MCAO) [17].