MPO and retinoblastoma: Both tonic herbs (GS, AR) and SR slightly increased body weight, alleviated the increases of DAI and MPO, and prevented the decrease of colon length/weight ratio induced by DSS (Fig. 1A–D), while DSS-induced symptoms were aggravated by RB as evidenced by higher DAI mainly attributed to more severe body weight loss, and lower colon length/weight ratio than the UC group.