In the primary tumor, the expression of all 12 markers (CD8, CD68, Foxp3, CD11c, CD163, CD66b, CD56, CD20, PD-L1, VEGFR-2, Ki67, IFN-γ) in the PT region was lower than that in the TF region (p < 0.05). The gene discussed is MKI67; the disease is neoplasm.