The multivariate Cox regression forest plot was drawn according to the results of multivariate analysis, from which it could be concluded that EZH2 expression acted as an independent prognostic factor for the survival of mesothelioma patients (HR = 2.63, 95% CI 1.02–6.79, P = 0.046) (Fig. 1B). This evidence concerns the gene EZH2 and mesothelioma.