For this purpose, we treated cells directly with recombinant IL12 and IL13, used at concentrations previously found in supernatant of cells exposed to serum from patients with delirium (IL12 delirium: 20 pg/ml and IL13 delirium: 25 pg/ml) or without delirium (IL12 without delirium: 3 pg/ml, IL13 without delirium: 4 pg/ml, Fig. 1f, g), with or without the JAK inhibitors. This evidence concerns the gene IL13 and delirium.