Results showed significantly higher levels of IL12 during the proliferation, and IL13 during the differentiation, in the supernatant of cells treated with serum from delirium patients vs non-delirium patients (IL12: 20.6 ± 2.7 pg/ml vs 2.8 ± 2 pg/ml, Fig. 3c, d; IL13: 24.6 ± 3 pg/ml vs 3.9 ± 3.1 pg/ml, Fig. 3e, f), with no differences between supernatant of cells treated with serum samples collected at Time point 1 or Time point 2 (IL12: group effect: p < 0.0001; time effect: p = 0.8, Fig. 3d; IL13: group effect: p < 0.0001; time effect: p = 0.9, Fig. 3f). The gene discussed is IL13; the disease is delirium.