IFNG and viral infectious disease: Indeed, the virus infection is now well-known for its ability to induce an over-reacting immune response (defined as “cytokine storm” syndrome) characterized by the production of multiple inflammatory cytokines and chemokines measurable in the periphery, including interleukin 2 (IL2), IL6, IL8, IL12, IL13, interferon-gamma (IFN-γ) and tumour necrosis factor-alpha (TNF-α) [11–13].