In contrast, TAMs in the TME of SCLC expressed high levels of TCF4, IL2RA, PLA2G7, GAL3ST4, PLTP, CMKLR1, ADAMDEC1, and MMP12 (Fig. 2h), suggesting an immunosuppressive feature,28 and thus providing potential targets for SCLC immunotherapies. The gene discussed is CMKLR1; the disease is small cell lung carcinoma.