We further investigated the chromatin remodeling of the typical NF-κB target gene loci, such as IFITs, CCLs, GBPs, HERCs, NFKB1, and TNFSF10. Figure 5g demonstrated that upon infection, a greater number of loops were formed in these regions, and the corresponding DoD was also reduced. This evidence concerns the gene NFKB1 and infection.