TNF and Hypertension: After further adjustments for APOE ε4 genotype, diabetes, hypertension, and hypercholesterolemia (model 2), these associations remained significant between TNF-α and VF (β = −2.41, p = 0.0007) and WLL (β = −1.03, p = 0.005) and between IL-6 and VF (β = −1.03, p = 0.004) and WLL (β = −0.60, p = 0.0024).