Secondly, negative correlations were observed in the group of melanoma-educated monocyte-derived cells: between 1) CD14 and IL-10-producing CD4+CD25+ cells activatory capacity, between 2) CD209, HLA-ABC, HLA-DR, and IL-8 production and IFNγ- or IL-10 producing T cell stimulatory potential, between 3) CD86 and TNFα/IL-6 production, and finally, between 4) IL-6 and IL-8 production and IFNγ-producing CD8+ T cells activatory capacity (Fig 6D and S7 Fig panel B). The gene discussed is CD4; the disease is melanoma.