FLI1 and neoplasm: This tumor is caused by a chromosomal translocation of the EWS RNA binding protein 1 (EWSR1) and the E-twenty-six (ETS) transcription factor family, which mainly consists of the Friend Leukemia integration 1 (FLI1), ETS-related gene (ERG), ETS translocation variant 4 (ETV4), or other kinds of ETS transcription factors [1, 2].