CD1C and rheumatoid arthritis: To better understand how transcriptional profiles of circulating CD1c+ cDC were related to the patterns present in the same cell subsets infiltrated in SF from RA individuals, we performed an additional RNA-Seq analysis of n = 3 RA and n = 3 calcium pyrophosphate deposition (CPPD) crystal–associated arthritis patients (Supplemental Table 2).