THBD and rheumatoid arthritis: A comparative gene expression analysis considering FDR-corrected significant P values and changes in log2 fold change of expression over 1.5 or less than –1.5 identified a total of 784; 1,078; and 781 significant differentially expressed genes (DEG) in Mo, CD1c+, and CD141+ cDC from RA compared with HC, respectively (Figure 2A and Supplemental Table 4).