Supporting this possibility, RNA-Seq and qPCR analyses confirmed that expression of IL-1β, IL-8, and MIP1α tended to be elevated in Mo and CD1c+ cDC but not CD141+ cells from SF samples of patients with RA compared with alternative synovial myeloid cells from individuals suffering CPPD crystal–associated arthropathy (Figure 4A and Supplemental Figure 6A). The gene discussed is CD1C; the disease is arthropathy.