RBM5 and non-small cell lung carcinoma: In this study, our results demonstrated that hsa_circ_0003176 inhibited the growth and metastasis of NSCLC in vitro and in vivo and elucidated that hsa_circ_0003176 regulated the malignant biological functions of NSCLC cells by targeting the expression of RBM5 through sponge adsorption of miR-182-5p in vitro, but hsa_circ_0003176 inhibiting NSCLC progression by regulating miR-182-5p/RBM5 axis has not been verified in animals.