For GSE110217, the targets of the DEGs were also enriched in PI3K/AKT and MAPK pathways, and the genes including NRAS, CCND1, AKT3, PTEN, E2F1, AXIN2, SOS2, TGFBR1, and LRP6 were enriched in hepatocellular carcinoma related pathway (Figure 2(c)). Here, AXIN2 is linked to hepatocellular carcinoma.