IGFBP3 and gastric adenocarcinoma: METTL3, WTAP, RBM15, RBM15B, YTHDC2, YTHDF1, YTHDF2, YTHDF3, HNRNPC, FMR1, LRPPRC, and IGFBP1 expressions were significantly higher in cluster B, while YTHDC1, IGFBP2, IGFBP3, FTO, and ALKBH5 had lower expression levels in cluster B.  Figure 4(e) depicts the heatmap of the association between the different clustering subgroups and the clinicopathological parameters of STAD patients.