GO enrichment analysis in this study showed that the differentially expressed genes were mainly distributed in mitochondrial ATP synthesis coupled electron transport, respiratory electron transport chain, oxidative phosphorylation, respiratory chain, mitochondrial intima, NADH dehydrogenase activity, oxidoreductase activity, etc. Meanwhile, core genes were mainly enriched in oxidative phosphorylation, nonalcoholic fatty liver disease, diabetic cardiomyopathy, myocardial contraction, and other pathways. The gene discussed is ENSG00000254051; the disease is metabolic dysfunction-associated steatotic liver disease.