Results indicated that high expression of ACOT2 was correlated with a significantly poorer prognosis compared with those exhibiting low ACOT2 expression (hazard ratio (HR) = 1.90; P=0.003) (Figure 2(b)), whereas ACOT1 (hazard ratio (HR) = 1.45; P=0.091) (Figure 2(a)), ACOT4 (hazard ratio (HR) = 1.32; P=0.193) (Figure 2(c)), and ACOT6 (hazard ratio (HR) = 1.13; P=0.567) (Figure 2(d)) was not significantly associated with poor OS in AML. The gene discussed is ACOT4; the disease is acute myeloid leukemia.