KEGG pathway enrichment analysis showed that differentially methylated genes (DMGs) in psoriasis were mainly enriched in the type I diabetes mellitus, autoimmune thyroid disease, bacterial invasion of epithelial cells, ECM-receptor interaction, tryptophan metabolism, insulin resistance, hematopoietic cell lineage, inflammatory bowel disease (IBD), cell adhesion molecules (CAMs), and other pathways (Figure 1(d)). Here, INS is linked to type 1 diabetes mellitus.