FAK mediates the FAK/PI3K/AKT/PKB, FAK/Ras/MAPK, FAK/STAT1, FAK/GSK, FAK/GTPase, and growth factor (TGF-β) signaling pathways, which in turn are interconnected, ultimately affecting protein and gene expression involved in proliferation, invasion, and migration of tumor cells [44–47]. The gene discussed is AKT1; the disease is neoplasm.