BUB1 and hepatocellular carcinoma: All 8 feature genes (BUB1, CCNB1, CCNB2, CCNA2, AURKB, CDC20, OIP5, and TTK) were observed to have a poor prognosis in HCC, suggesting that the 8 feature genes could be a useful biomarkers of HCC prognosis (Figure 5(e)).