The fraction for dendritic cells activated, mast cells activated, and neutrophils in the IDD group was remarkably higher than those in the normal group, while the fraction of some cells was obviously lower than that of the normal group, such as T cells CD4 memory resting, NK cells activated, and macrophage M0 (Figure 10(c)). This evidence concerns the gene CD4 and intervertebral disk degenerative disorder.