Although mice from the PRL.Cre group survived 5 months shorter, quantitative image analysis revealed a 1.4-fold higher tumor burden (P = 0.0191), which was mostly attributable to an increased number of tumors (3.0-fold, P = 0.0017) that were only slightly smaller in size compared to tumors from PR.Cre mice (0.61-fold, P = 0.0285; Fig. 7c). The gene discussed is PRL; the disease is neoplasm.