DNM1L and hepatocellular carcinoma: It has been reported that increasing mitochondrial fission mediated by upregulated Drp1 improves the proliferation of hepatocellular carcinoma (HCC) cells mainly by promoting the G1/S phase transition of the cell cycle, which indicates that manipulating Drp1-dependent mitochondrial fission could be a potential method for suppressing HCC tumor growth [47].