We used the autorefraction measurements at 3 mm diameter to derive measures of clinical interest, namely, mean corneal refractive power (mCRP), corneal astigmatism, and refractive astigmatism (Supplementary Methods) and checked for association with ANGPTL7. We observed a significant association with increased mCRP (betaallelic = 0.16 SD, P = 1.1 × 10–13, Table 1) but no association with corneal or refractive astigmatism. Here, ANGPTL7 is linked to Corneal astigmatism.