For instance, SLC38A3 was reported to be upregulated in metastatic non-small cell lung cancer and related to poor prognosis30; FST is known to be associated with tumorigenesis, progression, metastasis, and angiogenesis of solid tumors31, and SERPINE2 promoted local invasion of pancreatic tumor cells in vivo28. Here, FST is linked to non-small cell lung carcinoma.