SERPINE2 and non-small cell lung carcinoma: For instance, SLC38A3 was reported to be upregulated in metastatic non-small cell lung cancer and related to poor prognosis30; FST is known to be associated with tumorigenesis, progression, metastasis, and angiogenesis of solid tumors31, and SERPINE2 promoted local invasion of pancreatic tumor cells in vivo28.