Cerebral vGluT2+ neurons also showed a CJD-specific down-regulation of ND-related pathways, as well as “ribosome” and “positive regulation of translation.” This was notable as we observed that these translation-related terms were up-regulated in all cell types in FFI, with the exception of cerebral vGluT2+, where they were unaffected, and were also up-regulated in PV+, SST+, and cerebellar Gad2+ neurons in CJD. This evidence concerns the gene GAD2 and Creutzfeldt Jacob disease.