It demonstrated that patients with AF‐related stroke had increased epicardial adipose tissue when compared to patients with ischemic stroke without AF, but this study displayed important limitations, namely measurement of epicardial adipose tissue only on the free wall of the right ventricle using echocardiography, the inclusion of non‐embolic stroke patients and absence of adjustment for important variables such as body mass index and NTproBNP. The gene discussed is NPPB; the disease is Stroke.