Like CTHRC1, COL11A1, MMP13, COL10A1, POSTN, OGN, SFRP4, FAP, ADAMTS16 and FNDC1 were all seen to significantly affect survival in cancers with “high” expression (top 75 percentile) relative to “low” (bottom 25 percentile) (Fig 5A). Here, SFRP4 is linked to cancer.