DDB2 and cancer: DDB1 associates with DDB2 then recruits HDAC1 (histone deacetylase 1) to the P1 core region located 2.2 kb downstream of BCP1 to deacetylate histone H3K9,14, inhibiting Bcl-2 transcription, stimulating the P53-independent apoptosis of cancer cells, and mediating the sensitivity of OC cells to chemotherapy [79].