The levels of VEGF-A in renal macrophages after AKI were, however, significantly increased in both AKI-KRM and AKI-mono, exceeding the levels of VEGF-A in the renal macrophages from the developing kidney, suggesting that macrophage-derived VEGF-A may play critical roles in the tissue repair and angiogenesis after AKI (Figure 1B). This evidence concerns the gene VEGFA and acute kidney injury.