Moreover, the percentage of Clec7a-CD163- M1 macrophages in the kidney was significantly reduced after AKI (Figures 2A, C), while the percentage of Clec7a+CD163- M1 macrophages, Clec7a+CD163+ M2 macrophages and Clec7a-CD163+ M2 macrophages in the kidney were all significantly increased after AKI (Figures 2A, C). Here, CLEC7A is linked to acute kidney injury.