Increased cytokines and chemokines such as IL-6, GM-CSF, IL-1a, IL-15, CXCL9 and CXCL10 and complement system components such as C3 were also observed from 6 to 36 months after infection in patients with chronic disease compared to with retrieved controls (12, 81, 82). Here, CXCL10 is linked to infection.