Although the prevalence of anti-DFS70 antibodies in SLE patients in our study differed from other studies, the frequency of monospecific anti-DFS70 antibodies was still low at 1.2% (10/851), which is consistent with the previously reported rate (0.4%–3.1%) (9, 12, 16). The gene discussed is PSIP1; the disease is systemic lupus erythematosus.