PRDM1 and cancer: Additionally, miR-23a was discovered to be a target of cancer cells in CD8 T cytotoxicity, and miR-23a expression in CD8+ T cytotoxicity inhibited the expression of B lymphocyte-induced maturation protein-1 (BLIMP-1), which is an important regulator required for the development and activation of T cells as well as their recruitment to the site of infection (53, 54, 73).