MICA and breast cancer: Overexpression of miR-519a-3p in BC resists apoptosis by interfering with apoptotic signals induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas Ligand (FasL) but also impairs the anticancer response of NK cells by downregulating NKG2D ULBP2 and MICA, which are important for the appropriate recognition and function of NK cells (96).