As for the acute colitis induced by DSS or TNBS, the proportion of CD11b+Gr-1+ MDSCs and its subsets (CD11b+Ly6C+ M- and CD11b+Ly6G+ G-MDSCs) also increased in spleens and lamina propria and positively correlated with intestinal inflammatory scores (54). Here, ITGAM is linked to colitis.