Immune cells and inflammatory molecules have been implicated in COVID-19 progression, including type I interferon (IFN) (22, 25, 27, 29), innate immune cells (12–14, 16, 18, 28), antibodies (31, 32), autoantibodies (33, 34), and pro-inflammatory cytokines (14, 17, 21, 23, 26, 35). The gene discussed is IFNA1; the disease is COVID-19.