PROS1 and Parkinson disease: In comparison with the healthy controls, the assay showed that the plasma concentrations of PROS1 and LCN2 both were enhanced in PD (PD: PROS1, 77.52 ng/mL, range 3.727–387.4 ng/mL; LCN2, 98.83 ng/mL, range 41.64–224.6 ng/mL) (HC: PROS1, 55.49 ng/mL, range 2.019–151.6 ng/mL; LCN2, 44.94 ng/mL, range from 14.25–143.2 ng/mL) (Figures 9B, C).