IL10 and Crohn disease: IL-10 producing iNKT cells recently identified in the intestinal lamina propria of Crohn’s Disease patients showed suppressive activity towards pathogenic CD4+ T cells, and the frequency of IL-10 producing iNKT cells in colon tissue of these patients correlated inversely with TH1 and TH17 cell frequency, and was associated with reduced disease severity, higher TGFB gene expression, and lower levels of inflammatory proteins (37).