CD8A and coronary artery disorder: This difference can be attributed to a strong decrease in CD8+ cytotoxic T cells (4.1 ± 2.8% for EH, vs 11 ± 5.6% for YH), which was also observed in the heavy smoker and CAD patient groups (6.1 ± 4.1% for HS, 5.1 ± 4.1% for CAD).